遺伝子操作で寿命を延ばす？！（Extend the life in the genetic manipulation? !）

東北大は６日、同大大学院の片桐教授（代謝学）らのグループが、遺伝子操作により平均寿命が通常より約３割長いマウスを作ることに成功したと発表した。
人間の長寿化の研究に役立つと期待される。６日発行の米医学誌「サーキュレーション」に発表した。
高血圧などで血管が傷つくと炎症を起こし、動脈硬化の要因となるため、研究チームは、血管の最も内側にある血管内皮細胞で炎症反応が出ないような遺伝子操作を行った。また、食事制限で活動を低下させることで寿命が延びることは知られているが、食事制限はしなかった。
通常は寿命が約１年９か月のマウスに対し、遺伝子操作で作ったマウス２０匹を比較したところ、平均寿命が約２年３か月と３割程度延び、最長で約２年８か月生きたものもいた。筋肉内の血流と活動量が上昇したという。人間に応用するには、かなりの長い時間を要することでしょうが長寿化の研究には役立つでしょうね。

6 Sun Tohoku University, has announced that these groups (metabolomics) Katagiri, Professor of the university graduate school, and was able to make the average life expectancy is about 30% longer than normal mice by genetic manipulation.

It is expected that useful to the study of human longevity. Was published in "Circulation" of the U.S. medical journal published six days.

For inflammation, which can cause hardening of the arteries and blood vessels are damaged such as hypertension, the research team was carried out genetic manipulation, such as no inflammatory response in vascular endothelial cells of blood vessels in the innermost. In addition, it extends life by reducing the activity in the diet is known, dietary restriction did not.

To the mouse is usually nine months about a year, 20 animals were compared to mice made ​​genetically, extends life expectancy by about 30 percent about two years and three months, or eight for about two years the longest life Mon was also living. That the increased amount of blood flow and activity in the muscle. To be applied to humans, the study of longevity, but that would take quite a long time I will help.