Successful mouse experiment to suppress the growth of malignant brain tumor called glioblastoma.

Kataoka professors from Tokyo large is successful in mouse experiments were injected with a small capsule that put the anti-cancer agent , suppress the growth of malignant brain tumor called glioblastoma .Cells constituting blood vessels in the brain are not pushed out easily a substance in blood . It can also be administered into the blood medicine , it is hard to reach tumors outside of the vessel , could not be expected significant therapeutic effect.( Nano- parts per billion ) of mice to produce a capsule of about , were implanted with glioblastoma human diameter 30 nanometers stick to specific molecules in the only surface and tumor , vascular cells surrounding it team I was administered intravenously . Then, the capsule escape out of the vessel through the stick to the walls of blood vessels of the tumor , and release drugs into the tumor cells.
I 'm now at a time when it can be such a thing . So it would be really time consuming to clinical human experimentation , but I want to promote research for practical use .


抗がん剤を入れた小さなカプセルを注射し、膠芽腫という悪性脳腫瘍の増殖を抑えるマウス実験に東京大の片岡教授らが成功した。
　脳の血管を構成する細胞は血中の物質を簡単には外に出さない。薬を血中に投与しても、血管の外にある腫瘍に届きにくく、大きな治療効果が期待できなかった。
　チームは腫瘍と、それを取り巻く血管細胞の表面だけにある特定の分子にくっつく直径３０ナノメートル（ナノは１０億分の１）ほどのカプセルを作製し、人の膠芽腫を移植したマウスの静脈に投与した。すると、カプセルは腫瘍の血管の壁にくっついて通り抜け血管の外に脱出、腫瘍細胞に入って薬を放出した。
　こんなことが出来る時代になったんですね。人間の臨床実験までには時間がかかることでしょうが、実用化に向けて研究を進めて欲しいですね。