Clinical studies to improve with the cell sheet to diminished hearing.

Kojima Professor of Jikei University School of Medicine ( otology ) and others begin to prospect in January next year , the clinical research to improve using the cell sheet to diminished hearing in severe otitis media .
Of regenerative medicine in the world 's first to create a sheet by taking a cell of the nose , transplanted into the ear .
Subjects , patients gradually dissolve the bones of the middle ear and surrounding " chronic otitis media with cholesteatoma " , tympanic membrane from sticking to the walls of the middle ear of " adhesive otitis media ." In severe cases , both perform the surgery to remove the affected area . However , because the mucous membranes involved in the tension of the tympanic membrane , even after surgery is removed , that the hearing does not return often . There also be a recurrent otitis media .
Property is close to the cells of the mucous membrane of the ear , the research team , focusing on the cells of the mucous membranes of the nose . Take the mucous membrane of one square centimeter from the patient's nose , and culture into a sheet in a month or a little less than 1 , it was planned clinical research to port to the location where you removed the affected area . It is expected to serve to the mucous membranes of the nasal mucosa to replace the ear .
I want to hope that hearing to return clinical research is going well . And I also expect that this method is established.


重症の中耳炎で低下した聴力を細胞シートを使って改善させる臨床研究を、慈恵医大の小島教授（耳科学）らが来年１月をめどに始める。
　鼻の細胞を採ってシートを作り、耳に移植する世界初の再生医療という。
　対象は、中耳周辺の骨が徐々に溶ける「真珠腫性中耳炎」と、鼓膜が中耳の壁に張り付く「癒着性中耳炎」の患者。どちらも重症な場合に、患部を除去する手術を行う。だが、手術をしても鼓膜の張りに関わる粘膜が取り去られるため、聴力が戻らないことが多い。中耳炎を再発することもある。
　研究チームは、耳の粘膜の細胞に特性が近い、鼻の粘膜の細胞に着目。患者の鼻から１センチ四方の粘膜を取り、１か月弱でシート状に培養、患部を取り除いた場所に移植する臨床研究を計画した。鼻の粘膜が耳の粘膜に代わる働きをすると期待される。
　臨床研究が上手くいって聴力が戻ることを期待したいですね。そして、この手法が確立することも期待します。