The success that from iPS cells, to produce a kidney tissue.

Research group of Kumamoto University has been able to iPS cells from human to become various tissues of the body , creating a kidney tissue .
Kidney tissue with a structure able to produce urine in the same manner as in the body of a human was possible , it is the first time in the world .
Group of Prof. Nishinaka village of Kumamoto University , has found that to examine in detail the process of kidney is shaped in the body of the mouse , five types of material , such as a protein called " activin " are involved .
Then, when it was added in portions to the stage of some of the substance of this five different iPS cells of humans, is that the kidney tissue steric about 2 mm size is was able in vitro . It is that the organization of the kidney , the main organization of the kidney , such as tubes called tubules and glomeruli is included, and that have a structure able to produce urine in the same way as kidney in the body . Organization of these kidneys was created is , it is the first time in the world .
It was considered a three-dimensional structure is essential " kidneys to function , but it 's made ​​in the test tube to be close to impossible . The future , Nishinaka Village Professor want to make a small kidney for transplant I am talking to . "
I want you to raise the pitch of research towards practical person who has a disease of the kidney because it is large .



体のさまざまな組織になるヒトのｉＰＳ細胞から、腎臓の組織を作り出すことに熊本大学の研究グループが成功しました。
ヒトの体内にあるのと同じように尿を作り出せる構造をもった腎臓の組織ができたのは、世界で初めてです。
熊本大学の西中村教授らのグループは、マウスの体内で腎臓が形作られる過程を詳しく調べ、「アクチビン」というたんぱく質など５種類の物質が関わっていることを突き止めました。
そして、ヒトのｉＰＳ細胞にこの５種類の物質をいくつかの段階に分けて加えたところ、試験管内で大きさ２ミリほどの立体的な腎臓の組織ができたとのことです。この腎臓の組織には、糸球体や尿細管と呼ばれる管など腎臓の主な組織が含まれていて、体内にある腎臓と同じように尿を作り出せる構造を持っているということです。こうした腎臓の組織が作られたのは、世界で初めてです。
西中村教授は「腎臓が機能するには立体的な構造が欠かせないが、試験管内で作るのは不可能に近いと思われていた。将来は、移植用の小さな腎臓を作れるようにしたい」と話しています。
　腎臓の病気を持っている方が多いですから実用化に向けて研究のピッチを上げてほしいですね。