Only succeeded in killing cancer cells（がん細胞だけを死滅させることに成功）

Director of Research Department research team Inagaki, Aichi Cancer Center Research Institute carcinogen control of La (cell biology) is 11 days, in laboratory cultures of in vitro, taking advantage of normal cells, to kill only cancer cells announced that it had succeeded. You are the future, and can be expected to lead to the development of new drugs and new treatments for cancer.

Cells of mammals, including humans, when you stop the growth, can lead to a protrusion on the surface called "primary cilia" has been known. The research team, and primary cilia are formed, from within the cell, focus is placed on the fact that the enzyme is reduced. When culture experiments, and artificially eliminate this enzyme, suddenly normal cells to form primary cilia, became "dormant" stomach to stay healthy growth.

On the other hand, cancer cells, but it was confirmed that the growth continues, the size of the growth, that were killed in cell division can not be good. The case of conventional cancer treatment, because that is the neck would affect not only cancer cells, normal cells up to around, may be an effective treatment method is found to be using this method only cancer cells I have.


愛知県がんセンター研究所・発がん制御研究部の稲垣部長（細胞生物学）らの研究チームは１１日、試験管での培養実験で、正常な細胞は生かし、がん細胞だけを死滅させることに成功したと発表した。今後、がんの新たな治療法や新薬の開発につながることが期待できるとしている。
　人間を含む哺乳類の細胞は、増殖を停止する際、表面に「一次線毛」と呼ばれる突起物を生じることが知られていた。研究チームは、一次線毛が形成さ れると、細胞内から、ある酵素が減少することに着目。培養実験の際、この酵素を人為的になくすと、正常細胞は突然、一次線毛を形成し、健康なまま増殖しな い「休眠状態」となった。
　一方、がん細胞は増殖が続くことを確認したが、増殖の際、うまく細胞分裂できずに死滅したという。従来のガン治療の場合、がん細胞だけでなく、周りの正常な細胞にまで影響を与えてしまうことがネックですから、この方法を使えばガン細胞だけに有効な治療方法が見出される可能性がありますね。