2014年3月21日金曜日

Situation in which confidence in the Advanced Clinical Research of Japan is lost further.

For paper that was presented at the American Society on the basis of clinical research data national project of Alzheimer's disease research of " J-ADNI " , the 20th , Sugishita Tokyo University professor is one of the authors is inappropriate to include tampering to 14% of the data as there were such cases , I was called by e-mail papers to withdraw 12 people co- author . There is a possibility that the trust in the Advanced Clinical Research of Japan swaying in the paper issue of withdrawal STAP cells are further loss .
While participation as responsible for the data validation in J-ADNI, Sugishita Mr. explore the features of the brains of patients with Alzheimer's disease in collaboration with 12 people Iwatsubo University of Tokyo and his colleagues to serve a Principal Investigator in the domestic leader in dementia research August 2013 , it was announced in Neuroradiology Journal of the United States the paper PET to be performed for about ( positron emission tomography ) .
Results Sugishita Mr. was verified to obtain a new material in the paper after the announcement , it was tampered with the inspection time in order to adapt to international procedures in the interview test to try ① storage is 39 cases of 274 cases in the data that was used to paper , 14% ③ subjects who had not obtained the consent of ② subject was the age of non-standard - it was inappropriate and that was found . I It would be nice If it is not the tip of the iceberg . Moral of the lowest of the researchers I might be have been lost . It is a situation that shakes the backbone of science nation "Japan" .


アルツハイマー病研究の国家プロジェクト「J―ADNI」の臨床研究データに基づいて米国学会誌で発表した論文について、筆者の1人である杉下東大教授が20日、データの14%に改ざんを含む不適切な例があったとして、共同筆者12人に論文撤回をメールで呼びかけた。STAP細胞の論文撤回問題で揺らぐ日本の先端医療研究への信頼がさらに失われる可能性がある。
 杉下氏はJ―ADNIにデータ検証の責任者として参画する一方、認知症研究の国内第一人者で代表研究者を務める岩坪東大教授ら12人と共同でアルツハイマー病患者の脳の特徴を探るために行うPET(陽電子放射断層撮影)に関する論文を2013年8月、米国の神経放射線学会誌に発表していた。
 杉下氏が論文発表後に新たな資料を入手し検証した結果、論文に使ったデータ274例中、14%の39例が①記憶を試す面談検査で国際的手順に合わせる目的で検査時間を改ざんした②被験者の同意を得ていなかった③被験者が基準外の年齢だった――など不適切だったことが判明したという。氷山の一角でなければ良いのですがね。研究者の最低のモラルが失われてきているのかもしれませんね。科学立国『日本』の屋台骨を揺るがす事態ですね。

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