Regenerative medicine of the uterus.

That the rats were excised part of the uterus , and porting the membrane of a protein of the cell as a " scaffold " , the part that has been resected to play , pregnancy becomes possible , clearly in the experimental research team of Keio University rang. That there is a possibility of the future , it can be applied to regenerative medicine of the uterus after the partially excised and treated cervix (total ) cancer . The 6th , I will be presented at the Japanese Society for Regenerative Medicine being held in Kyoto .
Cells are making organs , are supporting layer, such as a fine mesh made ​​of a protein, such as collagen becomes " scaffolding " . Remove the rat uterus , Maruyama - Keio lecturer ( obstetrics and gynecology ) et al , taken only membrane portion melt the cell . Was partially excised rat uterus of yet another , and when transplanted to apply the film there , a new cell is fixed to the membrane gradually , cutting part is played . All four animals that were implanted is natural pregnancy , the fetus has grown steadily .
The membrane obtained by removing the cell , there is no rejection basically be implanted . Possibility that can be reproduced by the uterus transplant " scaffold has been shown . Maruyama instructor of a patient, such as adenomyosis that and cervical cancer in the future , advanced in part , tissue of the endometrium is able to muscle speak added, " may be applied to the uterus playback . It is a good light to the pregnancy and spread .



子宮の一部を切除したラットに、細胞の「足場」となるたんぱく質の膜を移植すると、切除された部分が再生し、妊娠も可能になることが、慶応大の研究チームの実験で明らかになった。子宮頸（けい）がんの治療などで部分切除した後の子宮の再生医療に将来、応用できる可能性があるという。京都市で開催中の日本再生医療学会で６日、発表する。
　臓器を作っている細胞は、コラーゲンなどのたんぱく質でできた細かい網のような膜が「足場」となって支えている。丸山・慶大講師（産婦人科学）らは、ラットの子宮を取り出し、細胞を溶かして膜部分だけ採取。さらに別のラットの子宮を一部切除し、そこに膜を当てるように移植すると、新たな細胞が徐々に膜に定着し、切除部分が再生した。移植した４匹すべてが自然妊娠し、胎児は順調に育った。
　細胞を取り去った膜は、移植しても基本的に拒絶反応がない。丸山講師は「足場の移植で子宮が再生できる可能性が示された。将来、部分的に進行した子宮頸がんや、子宮内膜の組織が筋肉中にできる子宮腺筋症などの患者の子宮再生に応用できるかもしれない」と話す。妊娠への光が広がっていくといいですね。