succeeded in cells from iPS, make pancreatic tissue efficiently.

That induced pluripotent stem cells of human grown cells and tissues various body from cells (iPS), make efficiently "islets" tissue of the pancreas to regulate blood sugar levels, Institute of Cell Biology child Oita Tokyo Professor Miyajima, a team of researchers has succeeded Watanabe by day 17.

When transplanted under the coating of the kidneys of mice in which the onset of type 1 diabetes can not make the hormone "insulin" to lower the blood glucose level is maintained blood glucose levels down to normal values​​, working well in vivo can be confirmed was. Presented at the Yokohama Japanese Society for Regenerative Medicine on October 22.

The idea of ​​the future development of the technology to produce large amounts of inexpensive and pancreatic islet cells from iPS, I want to use in transplantation therapy for patients with diabetes. I want to recommend further research to establish the technology to mass produce inexpensive and towards the clinical studies.


体のさまざまな細胞や組織に成長させられる人間の人工多能性幹細胞（ｉＰＳ細胞）から、血糖値を調節する膵臓の組織「膵島」を効率よく作ることに、東京大分子細胞生物学研究所の宮島教授、渡辺研究員のチームが１７日までに成功した。
　血糖値を下げるホルモン「インスリン」を作れない１型糖尿病を発症させたマウスの腎臓の皮膜の下に移植すると、血糖値が正常な値に下がって保たれ、生体で十分に働くことが確認できた。２２日に日本再生医療学会（横浜市）で発表する。
　今後はｉＰＳ細胞から安価で大量に膵島を作る技術を開発し、糖尿病患者への移植治療に利用したい考え。臨床実験に向けて安価で、かつ大量に作る技術を確立すべく更なる研究をすすめてほしいですね。