Gene acts as an oncogene called "RAC1" has mutated.

And found a strong oncogene cause multiple cancers such as malignant melanoma skin cancer and high-grade breast cancer, Jichiidai team has announced the electronic version of the U.S. National Academy of Sciences dated 5. I am with the results that lead to the development of new anticancer drugs that target this gene.

Team, the analysis method was originally developed by cancer cells in patients with fibrosarcoma 30s. I have discovered a gene that acts as an oncogene called "RAC1" has mutated, has become a major cause of this fibrosarcoma.

Also, other than fibrosarcoma, found that breast cancer and some six species of malignant melanoma, and pancreatic cancer, there is a mutation in the gene and its fellow RAC1. By all means, I hope will lead to the development of anti-cancer drugs to overcome the powerful gun.



乳がんや悪性度の高い皮膚がんの悪性黒色腫など複数のがんの原因になる強力ながん遺伝子を発見したと、自治医大のチームが５日付の米科学アカデミー紀要電子版に発表した。この遺伝子を狙った新たな抗がん剤の開発につながる成果としている。
　チームは、３０代の線維肉腫患者のがん細胞を独自に開発した手法で分析。「ＲＡＣ１」という遺伝子が変異してがん遺伝子として働き、この線維肉腫の主な原因となっていることを突き止めた。
　また、線維肉腫以外でも、悪性黒色腫や一部の乳がん、膵臓がんなど６種のがんで、ＲＡＣ１やその仲間の遺伝子に変異があることを発見。ぜひ、強力なガンに打ち勝つ抗がん剤の開発につながっていくといいですね。