Succeeded for the first time in the world to make eggs from (new stem cell) of mouse iPS cells.

To make eggs from (new stem cell) of mouse iPS cells that can change into a variety of tissues and organs, a research team from Kyoto University Professor Saito has succeeded for the first time in the world. This egg from a healthy child was born.

Because of the use of a cell culture method special, can be applied to people immediately is not possible, but last year, the team has also succeeded in preparing the sperm of a mouse, there is a possibility that in the future can be used to study infertility .

IPS cells produced from the skin of the first female mice, Prof. Saito made ​​the basis of the sperm and the egg "primordial germ cells". Incubated with somatic cells of the ovary grow underlying eggs were removed and cells, from mouse embryonic another female. When transplanted into ovaries of mature females it has grown to be the egg primordial germ cells after 4 weeks. It seems to make a substance that the body cells are grown in eggs. Furthermore, when the in vitro fertilization the sperm collected from healthy male into an egg that could be, were transplanted into the oviduct of the female mature mice about 10, three mice of healthy children that I was born from two dogs. Generation of their children were born.

You'll also need further study, for women who suffer from infertility might be good news.



様々な組織や臓器に変化できるマウスのｉＰＳ細胞（新型万能細胞）から卵子を作ることに、斎藤・京都大教授らの研究チームが、世界で初めて成功した。　この卵子からは健康な子どもが誕生した。
　特殊な細胞培養法を用いているため、直ちに人に応用することはできないが、チームは昨年、マウスの精子作製にも成功しており、将来的には不妊症研究に利用できる可能性がある。
　斎藤教授らはまず雌のマウスの皮膚からｉＰＳ細胞を作製、卵子や精子のもとになる「始原生殖細胞」を作った。この細胞と、別の雌のマウスの胎児から取り出した卵子を育てる卵巣のもとになる体細胞を一緒に培養。これを成熟した雌の卵巣に移植すると、４週間後に始原生殖細胞が卵子に成長した。体細胞が卵子に成長させる物質を出しているらしい。さらに、できた卵子に健康な雄から採取した精子を体外受精させ、約１０匹の成熟した雌の卵管に移植したところ、２匹から健康な子どものマウス３匹が誕生した。その子どもの世代も生まれた。
　更なる研究が必要でしょうが、不妊症に悩む女性にとっては朗報になるかもしれませんね。