Hemostasis technique for efficiently using particle

Developed by these groups (Microbiology Immunology), was confirmed in animal experiments, Associate Professor of Boeiidai Kinoshita, a technique for hemostasis effectively using nano-sized particles. When these particles into the blood, making the blood clot that has attracted platelet function to stop the bleeding. It can now be used to people in the future, it helps you to eliminate the lack of large-scale disasters transfusion.

The intravenous injection of a solution of nanoparticles was wearing some of the proteins involved in hemostasis, thrombosis make efficiently collect platelets remaining was bleeding slightly, you stop the bleeding. In experiments with rabbits in which the massive bleeding from the liver, in 9 of 10 cases that were not administered platelet died within 24 hours, 10 patients with hemostasis in this technique I survived all. There were no side effects such as thrombosis and myocardial infarction (fast) pulmonary infarction. I want you to proceed with further research toward practical use because there are no side effects of blood clots sounds good, but must be confirmed in clinical practice.



ナノサイズの粒子を使って効率的に止血する技術を、防衛医大の木下准教授（免疫微生物学）らのグループが開発し、動物実験で確認した。この粒子を血液に入れると、出血を止める働きがある血小板を集めて血栓をつくる。将来的に人に使えるようになれば、大規模災害時の輸血不足の解消に役立つという。
　止血に関与するたんぱく質の一部をつけたナノ粒子の溶液を静脈注射すると、出血したところにわずかに残った血小板を効率的に集めて血栓をつくり、止血する。肝臓から大量出血させたウサギを使った実験では、血小板を投与しなかった１０例中９例は２４時間以内に死んだが、この技術で止血した１０例はすべて生き残った。肺梗塞（こうそく）や心筋梗塞など血栓症の副作用もみられなかった。 血栓による副作用がないという点がいいですね、臨床での確認が必要ですが実用化に向けて更なる研究を進めて欲しいですね。