Development of treatment and prevention of Alzheimer's disease.

In animal studies to reduce protein that causes Alzheimer's disease by accumulating in the brain the "amyloid beta", research team of Hiroshima and Hokkaido University was successful. The future, it could lead to the development of treatments and prevention of Alzheimer's disease.
Alzheimer's disease, which lead to such as memory impairment, that it becomes a mass gradually amyloid beta that it became impossible to decomposition in the brain to accumulate, damaging nerve cells are one of the causes.
Among particles made ​​of such as a membrane of lipids "exosomes", Yuyama Assistant Professor and colleagues Igarashi Professor of Hokkaido University Graduate School of Advanced Biosciences Research Institute, focused on the fact that those made by nerve cells to bind to amyloid beta were.
Injection 2 weeks exosomes brain of mice 4 months old genetically engineered to amyloid beta is made in excess, it was found that as compared to mice not injected, less about 45% on average amyloid beta.
In practical use, a considerable amount of time is likely to take in the near future, I might become to be able to disease prevention, including such as dementia.


脳内に蓄積することでアルツハイマー病の原因となるタンパク質「アミロイドベータ」を減少させる動物実験に、北海道大や広島大の研究チームが成功した。今後、アルツハイマー病の予防や治療法の開発につながる可能性があるという。
　記憶障害などを招くアルツハイマー病は、脳内で分解しきれなくなったアミロイドベータが蓄積して次第に塊になり、神経細胞を傷つけることが原因の一つとされる。
　北海道大大学院先端生命科学研究院の五十嵐特任教授や湯山特任助教らは、脂質の膜などでできた粒子「エクソソーム」のうち、神経細胞で作られるものがアミロイドベータと結合することに着目した。
　アミロイドベータが過剰に作られるよう遺伝子操作した生後４カ月のマウスの脳にエクソソームを２週間注入すると、注入していないマウスに比べ、アミロイドベータが平均で約４５％少ないことを突き止めた。
　実用化には、かなりの時間が掛かりそうですが、近い将来、認知症なども含めた病気の予防ができるようになるのかもしれませんね。

Won for the first time as a Japanese.

9th World Sudoku Championship vying for the world champion puzzle using a number of "Sudoku" was held in London this month, Morinishi's Tokyo University graduate student has won the first Japanese. The 20th, the British puzzle Association announced.
Morinishi's has been enrolled in the University of Tokyo Graduate School of Engineering Sciences, there is a winner of another government agencies in China sponsored by any "world championship" until now.
In this tournament, which was held until the 14th of this month, Japan played a victory for the third time after two years in team competition. Second place Germany, third place was China.
Sudoku puzzle game named in Japan. The mass of 9 × 9, I fill in the numbers 1-9 so that the numbers do not overlap in the same column. Congratulations on winning for the first time.

数字を使ったパズル「数独」の世界王者を争う第９回世界数独選手権が今月ロンドンで開かれ、東大大学院生の森西さんが日本人として初めて優勝した。英国パズル協会が２０日、発表した。
　森西さんは東大大学院工学系研究科に在籍しており、これまで中国の政府系機関が主催する別の「世界選手権」でも優勝経験がある。
　今月１４日まで開かれた今回の大会で、日本は団体戦でも２年ぶり３度目の優勝を果たした。２位はドイツ、３位は中国だった。
　数独は日本で名付けられたパズルゲーム。９×９のマスに、同じ列に数字が重複しないように１から９までの数字を埋める。初めての優勝おめでとうございます。

New technique that can diagnose cancer at an early stage in the blood test.

The 18th, the National Cancer Research Center announced in collaboration with companies and research institutions in the country, and begin the research and development of new techniques that can diagnose cancer at an early stage in the blood test. 
When it comes to cancer, the fact that the type and amount of a substance called "micro RNA" changes in the body. 
To participate, companies and research institutes, "New Energy and Industrial Technology Development Organization (NEDO)", such as Toray independent administrative agency of the Ministry of Economy, Trade and Industry. Micro-RNA is very small substances to regulate the function of a gene. In recent years, by cancer, that the micro-specific RNA is detected many has been found. Was determined for this material is not decomposed in a period of time blood, to be available for inspection. 

In the study, subject to the 13 types of cancer, such as pancreas and pancreatic cancer, breast cancer, and to analyze the blood of 65,000 persons, to investigate the relationship between the micro-RNA and cancer. Study period is five years. According to Ochidani and molecular cell therapy research field length of the Center Research Institute, Research Results at small being able to determine the cancer with an accuracy of 90% or more by examining the micro-specific RNA in breast cancer are also out, first, it aims to develop tests for breast cancer. To practical, month and year of how much I would do or take.

国立がん研究センターは１８日、国内の研究機関や企業と共同で、血液検査で早期にがんの診断ができる新手法の研究開発を始めると発表した。
　がんになると、体内で「マイクロＲＮＡ」という物質の種類や量が変化することを利用する。
　参加するのは、経済産業省所管の独立行政法人「新エネルギー・産業技術総合開発機構（ＮＥＤＯ）」、東レなどの企業や研究機関。マイクロＲＮＡは、遺伝子の機能を調節する非常に小さい物質。近年、がんによっては、特定のマイクロＲＮＡが多く検出されることが分かってきた。この物質は血液中で一定期間分解されないため、検査に利用できると判断した。
　研究では、乳がんや膵臓すいぞうがんなど１３種類のがんを対象に、６万５０００人分の血液を解析し、がんとマイクロＲＮＡとの関連を調べる。研究期間は５年。同センター研究所の落谷・分子細胞治療研究分野長によると、乳がんでは特定のマイクロＲＮＡを調べると９割以上の正確さでがんを判定できるという少人数での研究成果も出ており、まずは乳がんの検査法の開発を目指すという。実用化するには、どれくらいの年月が掛かるんでしょうかね。

The next president.

The next president global academic institutions of mathematics of the "International Mathematical Union", forest compound sentences professor of Kyoto University Research Institute for Mathematical Sciences was elected. It is the first time in Japanese, term of office for four years from January 2015. And determined by the General Assembly which was held in South Korea in the 11th, the 12th, the institute announced.
International Mathematical Union, has announced called "Nobel Prize of mathematics" and "Fields Medal".
Professor Mori Nagoya City from According to the institute. Kyoto University Faculty of Science after graduation, through the United States Harvard assistant professor, and professor at Nagoya University, incumbent from 1990. Guru of algebraic geometry, was awarded the Fields Medal in 1990. It has been awarded is given to researchers who gave outstanding achievement in the field of natural science, "Fujiwara Award" in 2004.
Upon president appointed, Professor Mori issued a comment "math since it has developed in many emerging economies around the world, including the. Asia bracing think the gravity of the situation, you want to contribute to the promotion," he said. It is an honor and the first Japanese. By all means, please Good luck.

数学分野の世界的学術機関「国際数学連合」の次期総裁に、京都大学数理解析研究所の森重文教授が選出された。日本人では初めてで、任期は２０１５年１月から４年間。１１日に韓国で開かれた総会で決定し、１２日、同研究所が発表した。
　国際数学連合は、「数学のノーベル賞」といわれる「フィールズ賞」を発表している。
　同研究所によると森教授は名古屋市出身。京都大学理学部卒業後、米ハーバード大助教授、名古屋大学教授などを経て、１９９０年から現職。代数幾何学の第一人者で、９０年にフィールズ賞を受賞。２００４年には自然科学の分野で優れた業績をあげた研究者に贈られる「藤原賞」を受賞している。
　総裁就任にあたり、森教授は「事の重大さに身が引き締まる思い。アジアを始め世界中の多くの新興国で数学が発展していますので、その振興にも寄与したい」とコメントを出した。日本人初とは名誉なことですね。ぜひ、頑張ってください。

Development of the camera of the world's fastest.

That it has developed a camera of the world's fastest that can be continuous shooting time each shorter than 1 second 1 trillionth, joint research team of Keio University and University of Tokyo announced in the scientific journal Nature Photonics electronic version of 10 date. In high performance thousand times greater than the conventional fast camera, and it may be possible to clearly photographed the chemical reaction or plasma phenomenon be taken so far been difficult.
1 sec 1 trillionth (1 picosecond), a slight time enough light to be seven and a half laps the earth in one second does not proceed only 0, 3 mm. This camera mechanism is broken into each wavelength further light corresponding to the flash that flashes 1 trillion or more times per second, and applied to the subject one after another to obtain a continuous image.
It is amazing technology, research and nuclear fusion it is likely to go largely behavior of the plasma is captured clearly.

１兆分の１秒よりも短い時間ごとの連写撮影ができる世界最高速のカメラを開発したと、東京大と慶応大の共同研究チームが１０日付の科学誌ネイチャーフォトニクス電子版に発表した。従来の高速カメラの千倍以上高い性能で、これまで捉えることが難しかったプラズマ現象や化学反応などを鮮明に撮影できる可能性があるという。
　１兆分の１秒（１ピコ秒）は、１秒で地球７周半もする光が０・３ミリしか進まないほどのわずかな時間。このカメラは、１秒に１兆回以上点滅するフラッシュに相当する光をさらに波長ごとに細かく分け、次々に被写体に当て、連写画像を得る仕組み。
凄い技術ですね、プラズマの振る舞いが鮮明に捉えられると核融合などの研究が大きく進みそうですね。

IT drug discovery.

Kowa Fujitsu and University of Tokyo, pharmaceutical company, was able to to take advantage of the supercomputer world's fastest class of RIKEN "today" the (Kobe), to prepare a candidate for anti-cancer agent.
In a method called "IT drug discovery", and is noted as a new technique of making efficient medicine expected high therapeutic effect.
The research team, focusing on the protein plays an important role in the growth on the surface of cancer cells. The entry of the protein "lock" as a "key", and was designed with supercomputers chemicals that suppress cell proliferation. It becomes possible to perform precisely By using supercomputers, complex calculations and the impact of water in the body forces and chemical proteins and attractive.
Design of chemical substances in the supercomputer takes charge of Fujitsu. I was verified Kowa or may be chemically synthesized in practice. University of Tokyo played and improvement of the design method. I'm now in the era of drug discovery can be efficiently by taking advantage of the supercomputer. Come and I want to regain the status of super fastest computer in the world.

東京大と富士通、製薬会社の興和は、理化学研究所の世界最速級のスーパーコンピューター「京」（神戸市）を活用して、抗がん剤の候補物質を作製することに成功した。
　「ＩＴ創薬」と呼ばれる方法で、高い治療効果が見込める薬を効率的に作る新たな技術として注目される。
　研究チームは、がん細胞の表面にある増殖に重要な役割を果たすたんぱく質に着目。たんぱく質の「鍵穴」に「鍵」のように入り込み、細胞増殖を抑える化学物質をスパコンで設計した。たんぱく質と化学物質が引き合う力や体内の水分の影響など複雑な計算を、スパコンを使うことで精密に行うことが可能になった。
　スパコンでの化学物質の設計は富士通が担当。興和が実際に化学的に合成できるか検証した。東大は設計方法の改良などを担った。スーパーコンピューターの活用して効率的に創薬ができる時代になったんですね。ぜひ、世界最速のスーパーコンピューターの地位を取り戻して欲しいですね。

Way of life that it is not old.

Japan is the life expectancy in the world, but according to this book actually in the world "bedridden superpower" even seems certain.
Even alive no matter how long, and I think we can enjoy life and what made ​​activities freely.
In this book, one book to propose a "way of life that is not old," that not only live longer simply.
Relationship of health and speed, time, you are covered up to influence the emotions, and how effective has on the aging if the motion of how much not only for food natto, broccoli, and red wine, and walk.
Those who by the mechanism of longevity that has been elucidated in scientific, would like to know more of three elements to stop the aging "How", "system" and "smile", please read by all means.


日本は世界一の長寿国ですが、本書によると実は世界一の「寝たきり大国」でもあるそうです。
いくら長く生きても、自由に活動できてこそ人生を楽しめるのではないでしょうか。
本書では、単純に長く生きるだけでない「老いない生き方」を提案する１冊。
納豆、ブロッコリー、赤ワインといった食べ物に関してだけでなく、歩くスピードと健康の関係、いつ、どれくらいの運動をすれば効果的なのか、そして感情が老化に与える影響まで網羅されています。
科学的に解明された長寿のメカニズムによる、老化を止める３つの要素「動」「制」「笑」について詳しく知りたいという方は、ぜひ読んでみて下さい。